Bone Abstracts

Vertebral fractures are an important cause of pain and disability in osteoporotic patients.The main goals of treatment of vertebral fractures are to alleviate pain, stabilize the fracture, prevent new fractures and reduce comorbidities.Although vertebral fractures are frequently asymptomatic most patients will require analgesic medication for acute pain related with vertebral compression or chronic pain due to kyphosis and posture ...

Pharmacologic treatment of patients with a high risk of fracture is mandatory. Nowadays there are many available options mostly with antiresorptive agents (bisphosphonates, SERMs, strontium ranelate, calcitonin, estrogens and denosumab) but also with anabolic agents (teriparatide) that have shown to reduce incidence of new fragility fractures. In the near future new drugs targeting different pathways and mediators involved in bone remodelling will be available.<p class="ab...